"Correlation of Serum Nitric Oxide, High Sensitivity C-reactive Protein and Lipid Parameters in Diabetics with and without Coronary Artery Disease."

Abstract

Coronary Artery Disease (CAD) and Diabetes Mellitus (DM) top the list among noncommunicable diseases. Nitric Oxide (NO) preserves normal vascular physiology. Uncoupling of endothelial nitric oxide synthase enzyme occurs in the blood vessels of diabetics leading to endothelial dysfunction and excessive production of superoxide anion causing decreased bioavailability of NO. Aim and Objectives: To assess the serum NO levels, highsensitive C-reactive Protein (hsCRP), lipid parameters and their association with CAD in diabetics. Material and Methods: The study comprises total 195 participants. There are three groups,