Amitraz Poisoning: Unusual Lethal Poisoning

Abstract

Background: Amitraz is a ectoparasiticide and pesticide used widely on animals and in agriculture. It contains triazapentadiene, a centrally acting alpha-2 adrenergic agonist. Though Amitraz is widely used worldwide, its poisoning is uncommon in humans. Children are frequently involved due to accidental exposure whereas in adults suicidal attempts are more common. Poisoning occurs via oral, dermal and inhalational routes. Case presentation: Case 1: We describe a case of Amitraz poisoning in a 21 years old young female. She developed bradycardia and hypotension and required oxygen support and intensive care unit stay. She had a quick recovery after she was treated symptomatically and was discharged well after 4 days. Case 2: Case of Amitraz poisoning in a 23 years old young male. He was unconscious but vitals were maintained. He required ventilatory support and intensive care unit stay. He had a late recovery after he was treated symptomatically and was discharged well after 6 days. Conclusion: There is currently no known antidote for amitraz poisoning and the management is mainly supportive and symptomatic. Public education on potential hazards of amitraz poisoning is very important for community health.