Abstract:
Subclinical hypothyroidism is defined as
a serum TSH concentration above the upper limit of
the reference range when serum T3 and T4 concentrations
are within reference ranges. Subclinical thyroid
disease is a laboratory diagnosis. Patients with
subclinical disease have few or no definitive clinical
signs or symptoms of thyroid dysfunction. It has been
associated with higher levels of some cardiovascular
risk factors. Despite some conflicting results, many
studies have found that subjects with subclinical hypothyroidism
have total cholesterol and low density lipoprotein
cholesterol levels higher than euthyroid subjects.
The association between subclinical hypothyroidism
and dyslipidemia is well known.