Abstract:
CronkhiteCanada
syndrome (CCS) is a rare syndrome first described in 1955. Since then, over 400
cases worldwide have been reported in the literature. The disease is characterized by diffuse
gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous
hyperpigmentation, diarrhea, weight loss, and abdominal pain. An autoimmune etiology is
suspected. The workup is based on history and physical examination,
