Abstract:
The study was undertaken to evaluate cytological changes that occur in the oral mucosa
of habitual Pan Masala eaters. Background: The present study was undertaken to find the various
morphological changes that occur in the oral mucosa of habitual Pan masala eaters. Methods: Samples from
250 individuals who were eating pan masala for more than 6 months and 250 non-eaters by cotton tipped
applicator by scraping the buccal mucosa. Smears were prepared and stained by papanicolou method Atleast
1000 cells were scanned per slide under high power. Result: Total 1,76,530 and 1,26,869 cells were counted in
all Test slides and control slides respectively. Statistically high significant difference was found between user
and control group. Conclusion: Finding are accumulating regarding the local genotoxic
