Oxidative stress and antioxidant status in chronic obstructive pulmonary disease patients.

Abstract

Chronic obstructive pulmonary disease (COPD) is associated with high incidence of morbidity and mortality. The imbalance between oxidants and antioxidants is thought to play an important role in the pathogenesis of COPD. A total number of 120 subjects comprising of 60 healthy controls and 60 COPD cases were studied. Among 60 COPD cases, 30 were chronic bronchitis patients and 30 were emphysema patients. In all the subjects, serum levels of Malondialdehyde (MDA) as a biomarker of lipid peroxidation and antioxidants like whole blood red