Abstract:
Glaucoma is now the second leading cause of blindness globally, after cataracts,
according to World Health Organization. Approximately 11.2 million Indians above 40
years suffer from glaucoma. Raised intra ocular pressure is an important risk factor for
development and progression of glaucoma. Therefore, intra ocular pressure measurement
is essential in ophthalmological assessment.
Perkins tonometer is portable, simple and also considered gold standard because it
is based on the same principles as the Goldmann applanation tonometer. But it needs
topical anaesthesia, fluorescence staining, needs a specialist to do procedure .Corneal
factors, like astigmatism, corneal curvature, and central corneal thickness, affect the
accuracy of applanation tonometer.
In measuring intra ocular pressure by Non-contact tonometer there is no need of
anaesthetic, staining, no effect of corneal factors and can be done by a non medical or
paramedical personnel.
The need of this study is to correlate intraocular pressure measured using Noncontact tonometers with Perkins applanation tonometer and to study reliability of the
Non-Contact Tonometer as screening tool, considering its advantages over Perkins in
Indian context where large numbers of patients have to be screened and risk of
transmission of infection is high.
Aims and Objectives of this study were
• To correlate the intraocular pressure by the Non contact tonometer with the
Perkins applanation tonometer.
x
Methods:
It is a comparative study on Patients attending outpatient Department of
Ophthalmology BLDEU’s Shri B M Patil Medical College, Hospital and Research
Centre, Bijapur, Karnataka from December 1st 2014 to 31st March 2016. With a minimum
sample size of 128, we had included 260 participants in our study. Data was collected
using a proforma, with the informed consent of the patient, followed by obtaining history
and routine ophthalmological examination. Patients were subjected to two methods of
tonometry – Non Contact Tonometry and Perkins Applanation Tonometry (Perkins under
topical anaesthesia with 0.5% Proparacaine eye drops). Non Contact Tonometer readings
were recorded first, then Perkins tonometer. Three readings were taken for each method
and mean calculated. The data was statistically analyzed using Paired T test and
Correlation co efficient. Sensitivity and Specificity were also calculated for the Non
contact tonometer.
Results:
The non contact tonometer showed excellent agreement with the Perkins
tonometer. The correlation coefficient of intraocular pressure measured by Non contact
tonometer and Perkins applanation tonometer is 0.879 and 0.894 for right and left eye
respectively with p value of <0.05 in our study participants (both male and female),
showed strong positive correlation between the intraocular pressure measured by Non
contact tonometer and Perkins applanation tonometer. The non contact tonometer also
scored high as an effective screening tool. The non contact tonometer showed high
sensitivity 95.5 and 94.3 for right eye and left eye respectively (right eye more than left
xi
eye) i.e. very few false negative results as well as high specificity 94.5 and 99.1 for right
eye and left eye respectively (left eye more than right eye) i.e. few false positive results;
thus coming across an excellent agreement with Perkins applanation tonometer, using an
intraocular pressure of more than or equal to 21 mm Hg with the Perkins applanation
tonometer as the standard criterion.
Interpretation & Conclusion:
The current study shows that the Non contact tonometer compares well with the
Perkins applanation tonometer (hand held version of gold standard Goldmann
applanation tonometer) and showing excellent agreement with it. The non contact
tonometer can be used as a reliable screening tool.