Abstract:
INTRODUCTION
Most primary and secondary level hospitals in developing countries provide
inadequate labor analgesia due to various medical technical and economic reasons.
This clinical trial was an effort to study the efficacy, safety, and feasibility of low
dose intravenous ketamine in labor analgesia. The phencyclide derivative Ketamine is
widely used as IV and IM anesthetic agent and is mediated through opiate receptor
and N-methyl D-asparate receptors. A systemic administration of ketamine produce a
obvious advantage over nacrotics in which major drawback is respiratory depression.
AIM AND OBJECTIVES
To study the efficacy of Ketamine in labor analgesia in following parameters.
1.Maternal outcome in form of duration & mode of delivery, complication of 3rd
stage of labor.
2.Fetal outcome inform of APGAR score.
3.To evaluate patient satisfaction about this method.
MATERIALS AND METHODS
A total of 120 parturients were consented and randomly assigned to receive
either IV ketamine or 0.9%NS. A loading dose of 0.2mg/kg over 30mins following by
an infusion of 0.2mg/kg/hr until delivery of the baby. The control group will be
infused with NS with similar volumes.