Abstract:
Background and objectives
The relation of pulmonary tuberculosis and development of altered OGT are
not well documented and very few studies have reported that the incidence of diabetes
mellitus in patients with pulmonary tuberculosis. The present study was aimed to find
the incidence of glucose intolerance in patients with pulmonary tuberculosis.
Methodology
This one year cross sectional study was conducted in the Department of
Medicine , Shri B M Patil Medical College , Vijayapur on patients with pulmonary
tuberculosis. A total of 75 patients with patients with positive sputum smear for acid
fast bacilli or chest x-ray features suggestive of pulmonary tuberculosis aged more
than 30 years and less than 65 years were selected for the study.
Results
The results showed majority of the patients were males (84%) with maleto
female ratio of 5.25:1. . The most commonest age group was 41-50 years (25.33%)
followed by age >60 years (21.33%). The commonest presentation of pulmonary
tuberculosis was cough and expectoration of sputum (100% each)followed by loss of
appetite (96.67% ) followed by fever(76%). AFB findings showed +++ in 29.33%
patients. On chest x-ray almost 60% of the patients had cavitatory lesions with
infiltration . In 18.67% and 16% of patients fibrotic changes and cavitatory lesions
without infiltration were noted.
Conclusion and interpretation
This study of 75 cases showed overall incidence of impaired glucose tolerance
as 17.33% in patients with pulmonary tuberculosis. Among 82.67% patients GTT was
normal (Fasting < 110 mg/dL and 2 hours < 140 mg/dL). In 13.33% of patients
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impaired glucose tolerance (Fasting < 126 mg/dL and 2 hours> 140 mg/dL) was
recorded and among 4% patients diabetes mellitus (Fasting >126 mg/dL and 2 hours >
200 mg/dL) was diagnosed. No statistically significant association of sex, age and
chest X-ray findings was seen in patients with pulmonary tuberculosis and diabetes
mellitus.
